Among the medieval liturgical manuscripts from Ashkenaz, the Nuremberg Mahzor takes a special place. Its size, its extraordinary selection of piyyutim and piyyut commentaries, and its lavish decoration that differs from the model used for many mahzorim in southern Germany make it a spectacular object. This aroused curiosity and interest, as reflected by those who are known to have viewed the manuscript, including Emperor Leopold I (1658–1705), who visited the Nuremberg Municipal Library in 1658, and several 17th and 18th century Christian scholars who wrote about the treasures of Nuremberg.
In the 19th century, several Jewish scholars studied the manuscript in Nuremberg, among them Leopold Zunz from Berlin and Rabbi Isaak Meier Eppstein from Jerusalem, culminating in the detailed study and description by Nuremberg rabbi Bernhard Ziemlich (1884–1886). Salman Schocken had hoped to acquire the manuscript already in 1934 and succeeded in adding it to his collection in 1951. The fact that during its 56-year stay at the Schocken Library in Jerusalem the Mahzor was rarely exhibited and not easily accessible to scholars and the wider audience shrouded the manuscript in mystery.