The Evolution of Medical Practice

In the second half of the twentieth century, the medical community adopted the scientific method as a basis for practice. It seemed that after thousands of years the way was paved for a regulated process: from the laboratory through the clinical trial to the patient's bed. But it soon became clear that the road is neither straight nor continuous. Clinical research only offers unequivocal answers in a few cases. The balance between benefit and risk does not end with a statistical calculation; A significant part of the consideration of the factors that determine the change of medical practice is based on values, worldview and interests. Many factors are involved in the path leading from the laboratory to the patient: scientists, doctors, pharmaceutical and technology companies, politicians, regulators, and at the end of the path stand the patients themselves. Each of these factors uses the means at its disposal to influence the final result - the diagnosis, treatment and follow-up of the patient. The path of progress from the laboratory to the patient is also not continuous: sometimes the intervals between steps are large, sometimes sudden jumps occur after a prolonged period of slowing down and even stopping. Scientific and clinical research depends on the initiative, skills and determination of the researchers, and not a little on coincidences and has no fixed timetables.

This book is dedicated to revealing the evolution of medical practice, to identifying fundamental changes in practice and to describing the winding way in which they were accepted and assimilated into the body of medical knowledge and the mutual relationship between the doctor and the patient.