Requiem for Aspirin

In October 2018, results of a randomized controlled trial showed an excess mortality mainly from cancer, among “healthy” people over the age of 70 who took aspirin, in contrast to many clinical studies previously published. This event was another record in the crisis in scientific medicine that has been unfolding before our eyes in recent decades.

In this book the author tries to trace the causes of the shocks that afflict the medical  knowledge base, and to offer solutions to strengthen and stabilize it.

This book includes four parts. The first part discusses aspirin as a test case for development of clinical research. The second part is devoted to a discussion of the seven foundations of modern clinical research while revealing the pros and cons of each and their relative contribution to the pursuit of scientific truth. In the third part, five groundbreaking discoveries are examined. In each of them, the process that led to the discovery is deciphered, emphasizing the findings making clinical research, on the way from bench to bedside, redundant. In the fourth part the author exposes the rules of the competition among scientist, and determines its impact on the conduct of research and its results.